Colour Atlas of Paediatric Haematology

Colour Atlas of Opthalmology

Atlas of Genetics and Cytogenetics in Oncology and Haematology

In eukaryotic cell nuclei genomic DNA interacts with histones to form nucleosomes; arrays of nucleosomes are packaged into chromatin fibers that constitute chromatin in interphase cell nuclei, chromatides and chromosomes in mitotic cells. In the chromatin of the cell nucleus chromosome territories can be distinguished occupying well defined nuclear subvolumes (for review see Cremer and Cremer, ...

Atlas of Genetics and Cytogenetics in Oncology and Haematology

The main scientific and technological advances that have increased our ability to act so as to influence biology and call into question our idea of what constitutes a human being, have been made in the fields of genetics, and of embryology and cell therapy. These two fields of knowledge have often been confused, but for the specialist involved in these kinds of research, they are entirely disti...

Atlas of Genetics and Cytogenetics in Oncology and Haematology

I. 3D organization of the chromatin in the interphase nucleus 1. Relationship of the chromatin with the nucleus structures 2. Notion of chromosomal territories 3. Topography of the territories 4. Interface between neighbor territories 5. Organization model of the chromatin in the interphase nucleus II. Relative evolution of the territories when compared to each other during the succession of th...

Atlas of Genetics and Cytogenetics in Oncology and Haematology

NF-κB is a transcription factor governing the expression of genes involved in the immune response, embryo or cell lineage development, cell apoptosis, cell cycle progression, inflammation, and oncogenesis. During past few years, tremendous attention has been focused on the upstream signaling pathways leading to the activation of this transcription factor. Many of these signaling molecules can s...